Flexeril (generically known as cyclobenzaprine) is a muscle relaxant and it’s most typically prescribed for short-term relief of muscle spasms. While many people find Flexeril useful for pain management and muscle tension relief, stopping the medication suddenly can lead to withdrawal. If you’re thinking about discontinuing this medication, it’s a good idea to understand Flexeril withdrawal symptoms before doing so. Keep reading to learn about Flexeril side effects so you can be better prepared in the event you choose to stop taking this drug.
Understanding Flexeril Withdrawal Symptoms
Flexeril targets the central nervous system to relax muscles and ease discomfort. Although it’s not considered addictive in the same way as opioids, the body can become accustomed to its effects. Therefore, if someone suddenly stops taking the medication after regular use, Flexeril withdrawal symptoms may appear, which may include both physical and psychological challenges. The potential withdrawal risks are why medical supervision is recommended when discontinuing this medication.
Pain Management and Chronic Pain Programs
Flexeril is often prescribed to help manage muscle spasms and related pain. However, rebound muscle tension, insomnia, or mood changes, and even a resurgence of the original pain could emerge when one stops taking the drug. Understandably, this can make the withdrawal process feel even more difficult.
That’s why a chronic pain management program is a good idea, because it can offer structured alternatives to muscle relaxants. These alternatives may include targeted physical therapy, gentle stretching routines, non-addictive pain medications, or mind-body techniques such as yoga and guided relaxation. These programs also address the mental health side of withdrawal, offering coping strategies for anxiety, irritability, or depression that may appear when pain returns.
Having a comprehensive plan can reduce health risks during withdrawal and can also help transition off Flexeril more smoothly.
Common Symptoms of Withdrawal from Flexeril
Physical Symptoms
Headaches: Many people report headaches during withdrawal, which may be related to changes in muscle tension or nervous system adjustment.
Rebound Muscle Pain and Stiffness: Since Flexeril is often prescribed for chronic pain due to muscle spasms, discontinuing it can lead to a recurrence of muscle tension, aches, or stiffness.
Fatigue and Lethargy: Some individuals feel physically drained or unusually tired during withdrawal as the body adapts to functioning without the medication.
Insomnia or Disturbed Sleep: Flexeril has sedative effects, so stopping it can lead to difficulty falling asleep or staying asleep.
Psychological Symptoms
Anxiety and Restlessness: The nervous system may feel overstimulated without Flexeril’s calming effects, leading to increased anxiety or agitation.
Depression or Low Mood: Emotional lows can surface during withdrawal, especially if pain or lack of sleep interferes with daily life.
Irritability and Mood Swings: Fluctuating emotions are common as both physical discomfort and nervous system changes affect mood stability.
Difficulty Concentrating (Brain Fog): Mental clarity can be disrupted, causing some individuals to feel foggy or less focused than usual.
How Long Do Flexeril Withdrawal Symptoms Last
Many people want to know how long Flexeril withdrawal symptoms last. That depends on factors such as dosage, frequency of use, and individual health. In many instances, symptoms begin within the first few days after stopping and can last one to two weeks. Then again, some may notice lingering discomfort, especially if they relied heavily on Flexeril for pain relief. This is why having medical supervision and a solid withdrawal plan is critical for a safe experience ensuring as little discomfort as possible. To get a better idea of duration and symptoms, here is a general Flexeril withdrawal timeline for reference:
Flexeril Withdrawal Timeline
First 24–48 Hours
During the first couple of days, individuals may experience mild rebound muscle tension, headaches, or irritability. Since Flexeril has sedative effects, some people also experience early sleep difficulties once the drug is out of their system.
Days 3–7
Withdrawal symptoms often peak in the first week. Muscle spasms, stiffness, and pain may return more intensely, sometimes worse than before starting the medication. Insomnia tends to become more pronounced, and some individuals report restlessness, fatigue, or heightened anxiety during this phase.
Weeks 2–4
Many of the acute physical symptoms, such as muscle aches and headaches, start to lessen by the second to fourth week. Nevertheless, lingering issues like disrupted sleep, mood swings, or difficulty concentrating may persist as the body continues to readjust without Flexeril..
Beyond 1 Month
For some individuals, especially those who used Flexeril long-term, psychological symptoms such as anxiety, low mood, or irritability may linger. Ongoing muscle discomfort may also continue, requiring supportive therapies and alternative strategies for pain management.
Managing Flexeril Withdrawal Symptoms
Successfully managing withdrawal from Flexeril often requires a combination of medical guidance, supportive therapies, and lifestyle changes. Here are a few suggestions to consider:
Medical Supervision: Doctors may recommend tapering Flexeril gradually rather than stopping abruptly. In some cases, alternative medications may be introduced to support Flexeril pain relief during the transition.
Supportive Therapies: Counseling, cognitive behavioral therapy, and support groups can help individuals manage psychological symptoms such as anxiety and depression.
Lifestyle Adjustments: Regular exercise, a healthy diet, adequate hydration, and good sleep hygiene can significantly enhance recovery and overall well-being during withdrawal.
How Neurish Wellness Can Help
The compassionate team at Neurish Wellness understands that discontinuing medications like Flexeril can be a daunting adjustment. Our clinical team offers personalized support for individuals experiencing Flexeril withdrawal symptoms, guiding you through the process with care and compassion.
We combine medical supervision, therapy, and holistic approaches, such as mindfulness, nutrition counseling, and physical rehabilitation, to help you manage pain and improve your overall quality of life. Whether you’re struggling with withdrawal symptoms or seeking long-term strategies for healing, our team is here to support you.
The Next Step
Withdrawing from Flexeril can be challenging, but you don’t have to go through it alone. By collaborating with healthcare professionals and seeking the right support, you can effectively manage symptoms and work toward achieving improved health. Contact Neurish Wellness today to learn more about our treatment options and recovery programs.
FAQs About Flexeril Withdrawal Symptoms
How long do withdrawal symptoms last from medication?
The length of withdrawal symptoms depends on the medication, dosage, and individual health factors. For many drugs, symptoms may last a few days to several weeks, though some people experience lingering effects for months.
What are the stages of withdrawal?
Withdrawal typically progresses through an early phase (mild discomfort as the drug leaves the system), a peak phase (intensified symptoms), and a recovery phase (gradual improvement). The duration and intensity of each stage vary depending on the medication and individual factors.
Why was Flexeril discontinued?
Flexeril was not formally banned but has become less commonly prescribed in favor of newer muscle relaxants with fewer side effects. Concerns about drowsiness, misuse, and limited long-term effectiveness contributed to its reduced use.
What reduces withdrawal symptoms?
Gradual tapering off Flexeril under medical supervision is the most effective way to reduce withdrawal symptoms. Supportive care, healthy lifestyle changes, and alternative therapies can also ease the transition.
Can Flexeril cause mental issues?
Yes, Flexeril can sometimes cause side effects such as confusion, drowsiness, or mood changes. Individuals may also experience anxiety, irritability, or depression as the body readjusts during withdrawal.
Does Flexeril cause serotonin syndrome?
Yes, in rare cases, Flexeril can contribute to serotonin syndrome, especially when combined with other medications that increase serotonin levels. Symptoms may include agitation, rapid heart rate, tremors, or confusion, and medical attention is required if they appear.
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Cole Dyar is the Executive Director & co-founder of Neurish Wellness. He has been working in the behavioral health field in operational, clinical, organizational, and managerial capacities for thirteen years. He holds a degree from the University of California, Santa Cruz in sociology and is a Licensed Advanced Alcohol and Drug Counselor (LAADC) as recognized by CCAPP. Cole holds a Master of Science in Industrial/Organizational Psychology including: Organizational Leadership and Design, a Post-Masters in General Marriage and Family Therapy, and is currently a doctoral candidate in MFT with an emphasis in Systemic Administration & Entrepreneurship.